These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effects of endocrinological function of antrum on acid secretion of parietal cell in patients with duodenal ulcer].
    Author: Miura K.
    Journal: Nihon Geka Gakkai Zasshi; 1989 Jun; 90(6):826-36. PubMed ID: 2796954.
    Abstract:
    Antral G and D cells were microscopically counted by the immunoperoxidase method in the resected stomachs of 18 patients with duodenal ulcer (DU group), 4 with recurrent duodenal ulcer after selective proximal vagotomy (SPV-REC group) and 6 with early gastric cancer in the corpus (control group). In DU and SPV-REC groups, preoperative acid secretion stimulated by the tetragastrin (Tg-MAO, Tg-PAO) was examined. In 9 patients of DU and SPV-REC groups, adrenalin stimulated acid secretion (Adr-PAO) and integrated gastrin response (Adr-PGO) were also examined. The G cell count in DU group (Tg-MAO greater than or equal to 20) and SPV-REC group were significantly more than in DU group (Tg-MAO less than 20) and control group. In DU and SPV-REC groups, a significant correlation was observed between Tg-PAO and total G cell count. In 9 DU patients, a significant correlation was observed between the total G cell count and Adr-PGO or Adr-PAO, between Adr-PGO and Adr-PAO or Tg-PAO and between Tg-PAO and Adr-PAO. The above results suggested that increase of antral G cell counts is one of the great cause of duodenal ulcer and recurrent ulcer after SPV, greatly affecting on increase of acid secretion intermediating serum gastrin. Both Tg-PAO and Adr-PAO were regarded as good index of functional G cell mass of the antrum.
    [Abstract] [Full Text] [Related] [New Search]