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  • Title: Aspergillosis of the sphenoid sinus simulating a pituitary tumor.
    Author: Larrañaga J, Fandiño J, Gomez-Bueno J, Rodriguez D, Gonzalez-Carrero J, Botana C.
    Journal: Neuroradiology; 1989; 31(4):362-3. PubMed ID: 2797432.
    Abstract:
    Sphenoidal aspergillosis is an unusual cause of sella turcica enlargement. Pituitary abscess secondary to Aspergillus had been reported. In the present case, a woman with sphenoid sinus aspergillosis mimicked a pituitary tumor. This patient survived her infection with intact pituitary function following a transsphenoidal approach. No postoperative amphotericine-B and 5-fluorocytosine were necessary. CT scan revealed a mass occupying the sphenoid sinus extending to the sella turcica. Factors that should alert the clinican to the presence of a sphenoidal and pituitary abscess in a patient with sella turcica enlargement are prior episodes of sinusitis, meningitis and immunosuppression and, as in the present case, hyperglycemia.
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