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  • Title: Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide.
    Author: Bailey RR.
    Journal: N Z Med J; 1989 Jul 26; 102(872):379-81. PubMed ID: 2797556.
    Abstract:
    Five patients with a steroid-responsive, frequently relapsing nephrotic syndrome who had failed at least one course of treatment with cyclophosphamide were all put into a long term remission with chlorambucil. One patient developed a severe neutropenia and herpes zoster and another with an epileptic tendency developed myoclonic jerks. The indications and potential hazards of using chlorambucil in this context are discussed.
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