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  • Title: Syphilitic Aortitis Presenting with Coronary Ostial Stenosis and Aortic Regurgitation.
    Author: Jadeed R, Paarmann R, Harringer W, El-Essawi A.
    Journal: J Heart Valve Dis; 2016 Jan; 25(1):18-20. PubMed ID: 27989079.
    Abstract:
    Bilateral coronary ostial stenosis without additional coronary artery involvement is a rare presentation of syphilitic aortitis, with most cases being identified post-mortem. Herein is presented a case of bilateral coronary ostial stenosis and aortic valve insufficiency caused by syphilitic aortitis without aneurysmal dilatation of the aorta. The patient underwent aortic root replacement and coronary artery bypass grafting. The intraoperative macroscopic findings raised the suspicion of an aortitis that was later confirmed to syphilitic aortitis on histological examination. It is of note that syphilis can be a cause of bilateral ostial stenosis in young adults with no predisposition to atherosclerosis, especially if combined with aortic insufficiency resulting from an isolated leaflet dysfunction.
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