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  • Title: Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with etanercept.
    Author: Vieira MA, Saraiva MI, Silva LK, Fraga RC, Kakizaki P, Valente NY.
    Journal: Rev Assoc Med Bras (1992); 2016 Nov; 62(8):718-720. PubMed ID: 27992009.
    Abstract:
    We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for fungi and acid-fast bacilli (AFB). After discontinuation of etanercept, the patient's condition improved. Although apparently paradoxical, cases of cutaneous and systemic sarcoidosis after anti-TNF medications have been reported in the literature, with very few cases presenting exclusive cutaneous involvement.
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