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  • Title: [Subpopulations of peripheral blood T-lymphocytes in patients with chronic glomerulonephritis].
    Author: Rakitianskaia IA.
    Journal: Urol Nefrol (Mosk); 1989; (4):55-8. PubMed ID: 2800080.
    Abstract:
    Patients with membranous proliferative glomerulonephritis in the presence of nephrotic syndrome of without it were investigated for subpopulation composition of T lymphocytes and their functional activity in pHA blast transformation test. Though no difference was revealed in E+- and Fc+-receptor occurrence, both spontaneous and PHA-induced malformation of autoreactive T cells were observed. The results justified the previous data on the deficiency in lymphopoiesis of undifferentiated cells with end deoxynucleotidyltransferase as a marker. In patients with nephrotic syndrome PHA-induced blast transformation test revealed a decrease in lymphocyte function.
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