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  • Title: Triterpene saponins and megastigmane glucosides from Camellia bugiamapensis.
    Author: Huong NT, Vien LT, Hanh TT, Dang NH, Thanh NV, Cuong NX, Nam NH, Truong LH, Ban NK, Kiem PV, Minh CV.
    Journal: Bioorg Med Chem Lett; 2017 Feb 01; 27(3):557-561. PubMed ID: 28011215.
    Abstract:
    Two new triterpene saponins, camelliosides I and J (1 and 2), two new megastigmane glycosides, camellistigosides A and B (3 and 4), and two known megastigmane glycosides, icariside B1 (5) and (6S,9R)-roseoside (6), were isolated from a methanol extract of the Camellia bugiamapensis leaves using various chromatographic separation techniques. Their structures were elucidated based on spectroscopic analyses, including HR ESI MS, CD, 1D and 2D NMR. Their inhibitory effects on LPS-induced NO production in RAW264.7 cells were evaluated. This is the first report of the chemical constituents and biological activity of C. bugiamapensis.
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