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  • Title: Low-temperature thermal reduction of suspended graphene oxide film for electrical sensing of DNA-hybridization.
    Author: Wang T, Guo HC, Chen XY, Lu M.
    Journal: Mater Sci Eng C Mater Biol Appl; 2017 Mar 01; 72():62-68. PubMed ID: 28024629.
    Abstract:
    A reduced graphene oxide (RGO) based capacitive real time bio-sensor was presented. Suspended graphene oxide (GO) film was assembled electrophoretically between the source and drain electrodes of a transistor and then reduced by annealing in hydrogen/nitrogen forming gas to optimize the surface functional groups and conductivity. The resonance frequency of the transmission coefficient (S21) of the transistor was observed to shift with deoxyribonucleic acid (DNA)-hybridization, with a detecting limit of ~5nM. The advantages of the bio-sensing approach include low-noise frequency output, solution based real time detection and capable of on-chip integration.
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