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  • Title: A new phytoecdysteroid from the roots of Achyranthes bidentata Bl.
    Author: Yang L, Jiang H, Yan ML, Xing XD, Zhang YY, Wei N, Yang BY, Wang QH, Kuang HX.
    Journal: Nat Prod Res; 2017 May; 31(9):1073-1079. PubMed ID: 28033715.
    Abstract:
    A new phytoecdysteroid compound, named Niuxixinsterone D (1), together with two known phytoecdysteroid compounds (2 and 3) were isolated from Achyranthes bidentata Bl.. The structure of the new compound was elucidated by extensive spectral analysis, including HR-ESI-MS, 1D and 2D NMR methods. Compounds 1-3 were tested for their inhibitory effects against LPS-induced NO production in RAW 264.7 macrophages, and compound 1 and 3 exhibited anti-neuroinflammatory activity with inhibited 29.7 and 26.0% NO production.
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