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  • Title: [Effects of peptide factors from right and left brain hemispheres of rats on amplitude-time characteristics of projective and interhemispheric evoked responses].
    Author: Dobrynin VP, Sovetov AN, Pogozheva EN, Lutsenko VK, Ter-Minasian MK.
    Journal: Biull Eksp Biol Med; 1989 Jul; 108(7):5-7. PubMed ID: 2804299.
    Abstract:
    Peptide extracts of the right and left hemispheres were applied to the projective (somatosensory and visual) and temporal associative regions of the left brain hemisphere in cats. In the zones of peptide application, evoked potentials (EP) in response to singular and coupled somatic, visual and transcallosal stimuli were registered. The data obtained showed that right and left peptide extracts had different effects on evoked potentials of the left hemisphere. Thus ipsilateral extract increased the amplitude of projective EP, decreased duration of their cycles and amplitude of transcallosal responses. Contralateral extract, on the contrary, activated interhemispheric inputs to brain cortex, suppressed thalamic inputs and increased multimodal properties of neurons. A differential approach to the problem of specific correction of pathological states of the right and left brain hemispheres is required. Right and left peptide extracts may be used in normalization of interhemispheric activity balance in compensatory-recovering processes.
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