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  • Title: [Regulatory effects of opioid peptides on bone marrow hematopoiesis in stress].
    Author: Gol'dberg ED, Dygaĭ AM, Zakharova OIu, Shakhov VP.
    Journal: Biull Eksp Biol Med; 1989 Aug; 108(8):216-9. PubMed ID: 2804327.
    Abstract:
    It was shown that inhibition of bone marrow hyperplasia disappear due to injection of leu-enkephalin and dalargin as well as the increase of plasma leu-enkephalin by means of D-phenylalanine on the immobilized mice. The effect of enkephalin on hematopoietic precursor cells may be realized by inhibition of T-lymphocytes migration to bone marrow. Besides, direct specific influence of dalargin on myelokaryocytes is observed.
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