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  • Title: High Incidence of Escherichia coli Strains Coharboring mcr-1 and blaNDM from Chickens.
    Author: Liu BT, Song FJ, Zou M, Zhang QD, Shan H.
    Journal: Antimicrob Agents Chemother; 2017 Mar; 61(3):. PubMed ID: 28069644.
    Abstract:
    This study investigated the characteristics of Escherichia coli isolates carrying mcr-1-blaNDM from a chicken farm in China. Of the 78 E. coli isolates, 21 clonally unrelated isolates carried mcr-1-blaNDM Diverse IncI2 plasmids disseminated mcr-1, while the dissemination of blaNDM was mediated by diverse IncB/O plasmids. More striking was the colocalization of resistance genes mcr-1 and blaNDM-4 in an IncHI2/ST3 plasmid, which might pose a great challenge for public health.
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