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  • Title: Calvarial bone regeneration using osteogenin.
    Author: Hollinger J, Mark DE, Bach DE, Reddi AH, Seyfer AE.
    Journal: J Oral Maxillofac Surg; 1989 Nov; 47(11):1182-6; discussion 1187. PubMed ID: 2809833.
    Abstract:
    This experimental study reports on the application of a partially purified noncollagenous protein extracted from cortical bone to restore craniotomy defects in Papio species (baboon). The partially purified protein (osteogenin) produced significantly more bone formation in calvarial wounds than was found in the untreated controls. There were no adverse tissue reactions from the implanted xenogeneic osteogenin.
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