These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Using chiral ionic liquid additives to enhance asymmetric induction in a Diels-Alder reaction.
    Author: Goodrich P, Nimal Gunaratne HQ, Hall L, Wang Y, Jin L, Muldoon MJ, Ribeiro AP, Pombeiro AJ, Pârvulescu VI, Davey P, Hardacre C.
    Journal: Dalton Trans; 2017 Jan 31; 46(5):1704-1713. PubMed ID: 28102400.
    Abstract:
    A bis-oxazoline ligand has been complexed using Cu(ii) and Zn(ii) trifluoromethanesulfonate and a range of chiral ionic liquid (CIL) additives based on natural products were used as a co-catalyst for a Diels-Alder reaction. The catalytic performance of these systems was compared for the asymmetric Diels-Alder reaction between N-acryloyloxazolidinone and cyclopentadiene with and without the presence of a CIL additive. In the absence of the CIL, both catalysts resulted in low enantioselectivities in conventional solvents and ionic liquids. However, whilst only a minor effect of the CIL was observed for the Cu based catalyst, in the case of the Zn based catalyst, significant enhancements in endo enantioselectivity of up to 50% were found on the addition of a CIL.
    [Abstract] [Full Text] [Related] [New Search]