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  • Title: [Clinical evaluation of a new oral cephem, cefpodoxime proxetil in children].
    Author: Meguro H, Arimasu O, Shiraishi H, Tajima T, Hiruma F, Nishimura S, Sugie N, Sugamata K, Abe T, Fujii R.
    Journal: Jpn J Antibiot; 1989 Jul; 42(7):1561-70. PubMed ID: 2810730.
    Abstract:
    Cefpodoxime proxetil (CPDX-PR, CS-807) was evaluated for its efficacy, safety and pharmacokinetics in children. CPDX-PR was effective in 93.6% of 47 cases with respiratory tract, middle ear, skin or urinary tract infections. Twice or 3 times daily administration of 3 mg/kg each was sufficient to treat streptococcal pharyngitis and Haemophilus influenzae infections. No severe adverse reaction was encountered in 52 cases treated with CPDX-PR. The serum half-life was approximately 2.17 +/- 0.24 hours after oral administration.
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