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  • Title: [An amino acid substitution determining G1m(x) allotypic marker].
    Author: Ito S, Suzuki K, Miyazaki T, Matsumoto H.
    Journal: Nihon Hoigaku Zasshi; 1989 Apr; 43(2):155-60. PubMed ID: 2810890.
    Abstract:
    We confirmed the amino acid substitution responsible for G1m(x) allotypic marker, which was estimated by Cook & Steinberg (Mol. Immunol. 16:555-558 (1979), by primary structure analysis of the C-terminal BrCN peptide from normal human IgG1 carrying G1m(x+) or G1m(x-). The results indicate that IgG1 carrying G1m(x) have glycine instead of alanine at position 431 (Eu numbering). And we discussed the epitope on tertiary structure of IgG1-Fc fragment.
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