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  • Title: Chronic Eyelid Edema Following Periocular Hyaluronic Acid Filler Treatment.
    Author: Yu JTS, Peng L, Ataullah S.
    Journal: Ophthalmic Plast Reconstr Surg; 2017; 33(6):e139-e140. PubMed ID: 28121721.
    Abstract:
    A 54-year-old woman received multiple injections of hyaluronic acid filler to the brow region to address volume loss over a 21-month period. She then developed significant pitting edema of both upper eyelids, which persisted for 6 years. Hyaluronidase (Hyalase) was injected into the subcutaneous brows and resulted in complete resolution of the edema within 2 days. This confirms that the hyaluronic acid injected into the brows was responsible for this patient's chronic eyelid edema. This case illustrates an unusual long-term complication of periocular hyaluronic acid filler.
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