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  • Title: [Strategy for Unresectable Pancreatic Cancer with Stenosis of the Duodenum - A Case Report].
    Author: Komagome M, Ninomiya R, Nakazawa A, Mitsui T, Maki A, Ozawa F, Beck Y.
    Journal: Gan To Kagaku Ryoho; 2016 Nov; 43(12):1656-1658. PubMed ID: 28133089.
    Abstract:
    Unresectable(UR)pancreatic cancer often causes duodenal obstruction. Case 1: A 58-year-old man was diagnosed with UR pancreatic cancer with obstruction of the 3rd duodenal portion. A duodenum 2nd portion jejunum bypass was performed, and FOLFIRINOX was introduced and continued over 6 months. Case 2: A 74-year-old man was diagnosed with UR pancreatic cancer with obstruction of the duodenum near the Treitz ligament. A duodenum 3rd portion jejunum bypass was performed, and gemcitabine plus nab-paclitaxel was introduced. After 8 courses of GN, adjuvant surgery was performed. Both patients resumed oral intake within a few days after bypass, their performance statuses(PS)were improved, and their body weights increased. Because a duodenal jejunum bypass is more physiological than a gastro-jejunum bypass and duodenal stent, stable ingestion is enabled, and they are stable enough for early initiation of chemotherapy.
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