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  • Title: Rosai-Dorfman Disease: Manifestations Outside of the Head and Neck.
    Author: Mar WA, Yu JH, Knuttinen MG, Horowitz JM, David O, Wilbur A, Menias CO.
    Journal: AJR Am J Roentgenol; 2017 Apr; 208(4):721-732. PubMed ID: 28140608.
    Abstract:
    OBJECTIVE: Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION: The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.
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