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  • Title: Physiological expression of pancreatic somatostatin receptors in 99mTc-HYNIC-TOC scintigraphy.
    Author: de la Cueva L, Lloro P, Sangrós MJ, López Vélez L, Navarro P, Sarria L, Álvarez S, Abós D.
    Journal: Clin Transl Oncol; 2017 Jul; 19(7):915-920. PubMed ID: 28144828.
    Abstract:
    PURPOSE: To describe the frequency of head and/or pancreas uncinate process uptake of 99mTc-HYNIC-TOC, to study its nature, and analyze its diagnostic value. MATERIALS AND METHODS: Retrospective evaluation of 47 consecutive 99mTc-HYNIC-TOC examinations was conducted. Head and/or pancreas uncinate process uptake was considered to be physiological in patients with normal CT at the same episode and in follow-up. It was analyzed if age or diabetes mellitus was justifying the existence or not of uptake. RESULTS: 32.5% patients showed uptake; 73% of them were mild. 84.6% patients with uptake have no pathology and 4% had neuroendocrine pancreatic disease at CT. Neither the age nor the diabetes mellitus established differences in patients without lesion. CONCLUSIONS: Near one-third of patients show physiological uptake by head and/or pancreas uncinate process at 99mTc-HYNIC-TOC scintigraphy. It seems that neither the diabetes nor the ages are factors that determine this physiological uptake.
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