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  • Title: Validation of cadmium-zinc-telluride camera for measurement of left ventricular systolic performance.
    Author: Coupez E, Merlin C, Tuyisenge V, Sarry L, Pereira B, Lusson JR, Boyer L, Cassagnes L.
    Journal: J Nucl Cardiol; 2018 Jun; 25(3):1029-1036. PubMed ID: 28194726.
    Abstract:
    BACKGROUND: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging. METHODS: 60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement. RESULTS: 48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques. CONCLUSIONS: CZT-SPECT is reliable for LVEF measurement.
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