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  • Title: Two cases of sudden death due to pulmonary tumor thrombotic microangiopathy caused by occult gastric carcinoma.
    Author: Ben Khelil M, Chkirbene Y, Azzouz H, Haouet S, Hamdoun M.
    Journal: Pathologica; 2016 Dec; 108(4):160-163. PubMed ID: 28195256.
    Abstract:
    We present two cases of occult gastric carcinoma associated to a large pulmonary tumors thrombosis microangiopathy (PTTM). The first case is a 28 years-old man. He was dead due to a respiratory failure. Autopsy showed a whitish indurated mass invading the stomach wall. Histological findings showed a primary "signet ring" gastric adenocarcinoma with pulmonary carcinomatosis and multiple PTTM and a heart metastasis. The second case is a 24 years-old pregnant woman. The main symptoms were nausea and stomach discomfort and they were seen as pregnancy signs. She was dead because of respiratory failure, 10 hours after a vaginal delivery. Autopsy showed the absence of any cause of death related to the delivery and the presence of a whitish indurated mass in the stomach. Histological findings showed a primary "signet ring" gastric adenocarcinoma, with pulmonary carcinomatosis and multiple PTTM.
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