These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Different cell clones in bone marrow and spleen of a patient with chronic myelocytic leukemia (CML) in blastic phase.
    Author: Olinici CD, Petrov L, Macavei I, Dobay O.
    Journal: Cancer; 1978 Dec; 42(6):2707-9. PubMed ID: 282004.
    Abstract:
    The chromosome study of a patient with chronic myelocytic leukemia in blastic phase revealed a 46,XY,Ph1/47,XY,Ph1,+8 cytogenetic constitution in bone marrow cells and a 46,XY,Ph1/48,XY,2Ph1,+19 cytogenetic constitution in spleen cells. As the cell clones exhibiting chromosome abnormalities in addition to the Ph1 chromosome evolved apparently independently, it is suggested that the acute transformation had a bifocal, myeloid and splenic origin.
    [Abstract] [Full Text] [Related] [New Search]