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  • Title: [Chronic vulvar lymphedema revealing Crohn disease in a teenage girl].
    Author: Aounallah A, Ghariani Fetoui N, Ksiaa M, Boussofara L, Saidi W, Mokni S, Sriha B, Belajouza C, Denguezli M, Ghariani N, Nouira R.
    Journal: Arch Pediatr; 2017 Apr; 24(4):346-349. PubMed ID: 28233720.
    Abstract:
    INTRODUCTION: Cutaneous Crohn disease is a rare cutaneous manifestation of Crohn disease in children. Herein is reported a case of persistent vulvar lymphedema revealing Crohn disease in a teenage girl. CASE REPORT: A 14-year-old girl presented with an 8-month history of persistent vulvar swelling associated with chronic macrocheilia. Dermatologic examination showed an inflammatory vulvar lymphedema, associated with perianal fissures and hypertrophic gingivitis. Vulvar skin biopsy revealed non-necrotizing granulomatous inflammation. Gastrointestinal endoscopy yielded no significant findings. The diagnosis of Crohn disease presenting as vulvar lymphedema was established. Oral metronidazole therapy resulted in partial improvement of cutaneous lesions beginning the 1st week. CONCLUSION: The originality of this case lies in the presentation of chronic macrocheilia with persistent vulvar lymphedema in a child, revealing Crohn disease without gastrointestinal involvement.
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