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  • Title: Structural studies of the serotype-f polysaccharide antigen from Streptococcus mutans OMZ175.
    Author: Linzer R, Reddy MS, Levine MJ.
    Journal: Infect Immun; 1987 Dec; 55(12):3006-10. PubMed ID: 2824381.
    Abstract:
    The serotype f antigen of Streptococcus mutans has been described as a rhamnose-glucose polysaccharide associated with the bacterial cell wall. In this study, the structure of serotype f polysaccharide was examined by analyses of the methylated derivatives of the antigen and the periodate-oxidized antigen. Methylated derivatives were characterized with a gas chromatograph-mass spectrometer. The polysaccharide appeared to have a backbone of alternating 1,3- and 1,2,3-linked rhamnose units. Branching occurred at the 3-position of the 1,2,3-linked rhamnose. Side chains were composed of terminal alpha-linked glucose units. A small proportion of longer side chains containing 1,2- and 1,6-linked glucose units were noted in some preparations; however, these determinants were not reactive with serotype f antisera.
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