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  • Title: [Morbus Hodgkin as a second malignancy in acute lymphoblastic leukaemia (author's transl)].
    Author: Wingen AM, Olischläger A, Kleihauer E.
    Journal: Klin Padiatr; 1979 Jan; 191(1):1-7. PubMed ID: 282452.
    Abstract:
    19 months after the clinical manifestation of acute lymphoblastic leukaemia, Hodgkin's disease, stage Ia, of the cervical lymphnodes developed in a 10 year old girl during continuous complete remission of leukaemia under chemotherapy. After a regional irradiation and after completing the antileukamic therapy the patient is at present off therapy, healthy and without signs of relapse of both malignant systemic diseases. The coincidence of acute lymphoblastic leukaemia in children with other malignant neoplasias is rare. The expected frequency of second malignancies and the theories concerning oncogenesis are shortly reviewed.
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