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  • Title: Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene.
    Author: Fischel-Ghodsian N, Nicholls RD, Higgs DR.
    Journal: Nucleic Acids Res; 1987 Nov 25; 15(22):9215-25. PubMed ID: 2825132.
    Abstract:
    We have characterised a cluster of CpG rich (HTF) islands in the alpha-globin complex and report here two unusual features: The human embryonic zeta 2-globin gene is associated with an HTF island within its 3' portion rather than at the 5' end. Furthermore at least two non-functional pseudogenes within the cluster (psi zeta 1 and psi alpha 2) are associated with CpG rich islands.
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