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  • Title: [Influential factors of iron deficient anemia among infants aged 8 months based on a case-control study].
    Author: Gao X, Yan Y, Xiang S, Li H, Tan S, He Q, Sha T, Liu S, Zeng G, Yan Q.
    Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2017 Feb 28; 42(2):202-207. PubMed ID: 28255124.
    Abstract:
    To study the status and influential factors of iron deficient anemia (IDA) among infants aged 8 months in Changsha City.
 Methods: A case-control study was performed in this research. The case group including 105 8-month-old infants definitely diagnosed as IDA based on standardized blood test. Four-times numbers of age- and genger-matched infants without IDA were selected as a control group. Chi-square test and conditional logistic regression was used to analyze the influential factors for IDA.
 Results: The incidence rate of IDA among infants aged 8 months in Changsha City was 14.7%. The risk factors were as follows: mother with anemia in late pregnancy (OR=3.540, 95% CI 1.898 to 6.601), mixed feeding within 6 months old (OR=1.682, 95% CI 1.099 to 2.574), artificial feeding within 6 months old (OR=4.162, 95% CI 1.343 to 12.896), complementary feeding before 6 months old (OR=1.423, 95% CI 1.022 to 1.982), complementary feeding at or after 7 months old (OR=4.415, 95% CI 2.150 to 9.064), recurrent respiratory tract infections within 8 months old (OR=2.878, 95% CI 1.224 to 6.764), and repeated diarrhea within 8 months old (OR=3.710, 95% CI 1.533 to 8.980).
 Conclusion: There is certain incidence rate of IDA among infants aged 8 months in Changsha City. To prevent the IDA among infants, we should treat mothers' anemia during pregnancy, advocate scientific feeding, encourage complete breastfeeding until 6 months old, add complementary food timely and reasonably, treat infants suffering from respiratory or digestive diseases actively. 目的：探讨长沙市8月龄婴儿缺铁性贫血状况及其影响因素。方法：采用病例对照研究，将8月龄规范化血常规检测明确诊断为缺铁性贫血的105例婴儿纳入病例组，按1:4个体匹配，发生1个新病例的同时选取4例同一街道、同一性别按相同标准诊断未发生缺铁性贫血的婴儿作入对照组，收集相关资料，运用χ2检验、条件logistic回归分析婴儿缺铁性贫血发生的影响因素。结果：长沙市8月龄婴儿缺铁性贫血发生率为14.7%。8月龄婴儿发生缺铁性贫血的危险因素包括：母亲孕晚期贫血(OR=3.540，95% CI：1.898~6.601)、6月龄内混合喂养(OR=1.682，95% CI：1.099~2.574)、6月龄内人工喂养(OR=4.162，95% CI：1.343~12.896)、6月龄前添加辅食(OR=1.423，95% CI：1.022~1.982)、7月龄及以后添加辅食(OR=4.415，95% CI：2.150~9.064)、 8月龄内反复呼吸道感染(OR=2.878，95% CI：1.224~6.764)、8月龄内反复腹泻(OR=3.710，95% CI：1.533~8.980)。结论：长沙市8月龄婴儿缺铁性贫血仍有一定的发生率，应改善母亲孕期贫血，提倡科学喂养，鼓励纯母乳喂养至6月龄，并及时合理添加辅食，积极治疗罹患呼吸系统和消化系统疾病的患儿，预防婴儿缺铁性贫血的发生。.
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