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  • Title: Light-induced changes in the content of inositol phosphates in squid (Loligo pealei) retina.
    Author: Brown JE, Watkins DC, Malbon CC.
    Journal: Biochem J; 1987 Oct 15; 247(2):293-7. PubMed ID: 2827625.
    Abstract:
    Illumination induced an increase in inositol polyphosphates, inositol 1,4-bisphosphate and inositol 1,4,5-trisphosphate, in the photoreceptors of the squid, Loligo pealei. There was a concomitant decrease in phosphatidylinositol 4,5-bisphosphate, but no light-induced change in any other phosphoinositide. None of these stimulus-induced changes were altered by treatment in vivo with pertussis toxin, which ADP-ribosylated a Mr-39000-peptide. These findings support the hypothesis that inositol 1,4,5-trisphosphate participates as either a messenger or a modulator in transduction in invertebrate photoreceptors.
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