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  • Title: Regulation of diacylglycerol kinase in the transition from quiescence to proliferation in Dictyostelium discoideum.
    Author: Jímenez B, Van Lookeren Campagne MM, Pestaña A, Fernández-Renart M.
    Journal: Biochem Biophys Res Commun; 1988 Jan 15; 150(1):118-25. PubMed ID: 2827662.
    Abstract:
    Diacylglycerol kinase and phosphatidylinositol kinase were examined in stationary phase D. discoideum amoeba induced to synchronously proliferate by dilution into fresh medium. Membrane bound diacylglycerol kinase activity showed a rapid and transitory 3-5 fold increase in the preproliferative interphase while phosphatidylinositol kinase activity was kept quite constant during the same period. The changes in diacylglycerol kinase activity seem to be due to a translocation of the enzyme from the soluble to the particulate cell compartments.
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