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  • Title: [Effect of UHF and ionizing radiation on the Na-K-ATPase activity of Ehrlich ascitic carcinoma cells].
    Author: Smirnov RV, Andreev VP, Aleksandrova RA, Chulkova GF, Miatliuk TB.
    Journal: Vopr Onkol; 1988; 34(1):69-73. PubMed ID: 2829435.
    Abstract:
    The levels of Na-K-ATPase were measured in a microsome fraction of Ehrlich ascites carcinoma cells immediately, 10 and 30 min after exposure to microwave (series 1), 7 Gy of gamma-radiation (series 2) and different sequences of complex application of the agents (UHF + gamma-radiation) (series 3), (gamma-radiation + microwave) (series 4). Immediately after exposure, enzyme activity showed a significant decrease in series 1 and 4 (ser. 1-64 and ser. 4-58% as compared with control, alpha less than 0.05). A similar tendency was observed in series 2 and 3 (ser. 2-76 and ser. 3-84% as compared with control, alpha less than 0.05). With further exposure, it remained practically unchanged in ser. 1 and 4; in ser. 2 and 3 it continued to decrease within 10 min (ser. 2-42 and ser. 3-61% as compared with control, alpha less than 0.05); then it increased somewhat (ser. 2-49 and ser. 3-69%, alpha less than 0.05). The most pronounced inactivation was observed after exposure to gamma rays. Application of the latter in conjunction with microwave-field heating was followed by a protective effect.
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