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  • Title: Isolation of human pancreastatin fragment containing the active sequence from a glucagonoma.
    Author: Sekiya K, Ghatei MA, Minamino N, Bretherton-Watt D, Matsuo H, Bloom SR.
    Journal: FEBS Lett; 1988 Feb 08; 228(1):153-6. PubMed ID: 2830133.
    Abstract:
    The primary structure of a human pancreastatin-like peptide was determined from a pancreatic glucagonoma. The 28-amino acid peptide was identified using a specific antibody raised against porcine pancreastatin 1-49 and showed a 75% sequence homology with porcine pancreastatin 22-49 and bovine chromogranin A 267-294. Several forms of pancreastatin-like immunoreactivity were found in human endocrine tumors of which the purified peptide was the smallest and contained the active sequence of pancreastatin.
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