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Title: [Effects of Meek skin grafting on patients with extensive deep burn at different age groups].
Author: Di HP, Niu XH, Li Q, Li XL, Xue JD, Cao DY, Han DW, Xia CD.
Journal: Zhonghua Shao Shang Za Zhi; 2017 Mar 20; 33(3):156-159. PubMed ID: 28316165.
Abstract:
Objective: To investigate the effect of Meek skin grafting on patients with extensive deep burn at different age groups. Methods: Eighty-four patients with extensive deep burns conforming to the study criteria were hospitalized in our unit from April 2011 to April 2015. Patients were divided into children group (C, with age less than 12 years old), young and middle-aged group (YM, with age more than 18 years and less than 50 years old), and old age group (O, with age more than 55 years old) according to age, with 28 patients in each group. All patients received Meek skin grafting treatment. The use of autologous skin area, operation time, wound healing time, and hospitalization time were recorded. The survival rate of skin graft on post operation day 7, complete wound healing rate in post treatment week 2, and the mortality were calculated. Data were processed with one-way analysis of variance, t test, and χ(2) test. Results: The use of autologous skin area of patients in group C was (5.1±1.0)% total body surface area (TBSA), significantly less than (8.3±1.0)%TBSA and (8.3±1.4)%TBSA in groups YM and O, respectively (with t values 32.900 and 52.624, respectively, P values below 0.05). The operation time, wound healing time, and hospitalization time of patients in group C were (1.368±0.562) h, (9.6±0.6) and (32±11) d, significantly shorter than those in group YM [(3.235±0.011) h, (16.9±2.6) and (48±12) d, respectively] and group O [(3.692±0.481) h, (17.3±2.6) and (46±13) d, respectively, with t values from 4.350 to 21.160, P values below 0.05]. The survival rate of skin graft of patients on post operation day 7 in group C was (92±15)%, significantly higher than (81±10)% and (72±12)% in groups YM and O, respectively (with t values 5.509 and 3.229, respectively, P values below 0.05). The above indexes in groups YM and O were similar (with t values from 0.576 to 22.958, P values above 0.05). Complete wound healing rate in post treatment week 2 and the mortality of patients in group C were similar to those in groups YM and O (with χ(2) values 0.365 and 0.122, respectively, P values above 0.05). Conclusions: Meek skin grafting can be used in the treatment of patients with extensive deep burns at different age groups, compared with the young and middle-aged and old patients, the effect in children was better. 目的： 探讨Meek植皮在不同年龄段大面积深度烧伤患者中的临床应用效果。 方法： 2011年4月—2015年4月，选择笔者单位收治的符合入选标准的大面积深度烧伤患者84例。根据年龄将患者分为儿童组(年龄小于12岁)、中青年组(年龄大于18岁且小于50岁)和老年组(年龄大于55岁)，每组28例。所有患者创面均进行Meek植皮治疗。统计患者使用自体皮肤面积、手术时间、创面愈合时间、住院时间，计算术后7 d移植皮片成活率、治疗2周创面完全愈合率、病死率。对数据行单因素方差分析、t检验、χ(2)检验。 结果： 儿童组患儿使用自体皮肤面积为(5.1±1.0)%TBSA，明显小于中青年组患者的(8.3±1.0)%TBSA和老年组患者的(8.3±1.4)%TBSA(t值分别为32.900、52.624，P值均小于0.05)。儿童组患儿手术时间、创面愈合时间和住院时间分别为(1.368±0.562)h和(9.6±0.6)、(32±11)d，明显短于中青年组患者的(3.235±0.011)h和(16.9±2.6)、(48±12)d以及老年组患者的(3.692±0.481)h和(17.3±2.6)、(46±13)d(t值为4.350～21.160，P值均小于0.05)。儿童组患儿术后7 d移植皮片成活率为(92±15)%，明显高于中青年组患者的(81±10)%和老年组患者的(72±12)%(t值分别为5.509、3.229，P值均小于0.05)。中青年组和老年组患者上述指标相近(t值为0.576～22.958，P值均大于0.05)。儿童组患儿治疗2周创面完全愈合率、病死率与中青年组和老年组患者无明显差异(χ(2)值分别为0.365、0.122，P值均大于0.05)。 结论： Meek植皮可以用于不同年龄段大面积深度烧伤患者的治疗，相对于中青年、老年患者，其对患儿的修复效果更好。.

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