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  • Title: The use of glucose dehydrogenase to monitor the integrity of microsomes.
    Author: Bublitz C, Steavenson S.
    Journal: Biochim Biophys Acta; 1988 Apr 14; 965(1):90-2. PubMed ID: 2831997.
    Abstract:
    Various concentrations of Tergitol NP-10 stimulate mannose-6-phosphatase and glucose dehydrogenase to the same extent in untreated rat liver microsomes. Thus, the latency of glucose dehydrogenase may be used as an alternative to mannose phosphatase as a measure of the integrity of the microsomal membrane. The advantage of using glucose dehydrogenase rather than mannose phosphatase to monitor microsomal integrity is that NADH is more easily measured than Pi.
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