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  • Title: Keratoacanthoma en plaque/nodule: A brief report of the clinicopathological features of five cases.
    Author: Misago N, Ansai SI, Fukumoto T, Anan T, Nakao T.
    Journal: J Dermatol; 2017 Jul; 44(7):803-807. PubMed ID: 28332728.
    Abstract:
    Keratoacanthoma (KA) is characterized by exoendophytic growth with a central keratin-filled crater, representing the crateriform architecture. We herein report five rare cases of KA without a central keratin-filled crater. These KA cases histopathologically showed that one or a few infundibular structures/isthmic lobules had their own open keratotic pores on the surface without a common merged keratotic plug/horn, clinically representing verrucous (keratotic) plaque/nodule, namely, "KA en plaque/nodule". KA rarely but on occasion does show verrucous plaque (or nodular) lesions without a central keratin-filled crater, as the notion that KA invariably shows crateriform architecture is nonsensical.
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