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  • Title: 5'-Nucleotidase in skin fibroblasts from patients with Duchenne muscular dystrophy.
    Author: Sinclair CE, Ecob-Prince MS, Pennington RJ.
    Journal: Biochem Med Metab Biol; 1988 Feb; 39(1):1-4. PubMed ID: 2833294.
    Abstract:
    The 5'-nucleotidase of plasma membranes of cultured skin fibroblasts from patients with Duchenne muscular dystrophy had a reduced affinity for its substrate, 5'-AMP. The Arrhenius plot of the temperature dependence of this enzyme activity was normal. There was no difference between patients and controls in the specific 5'-nucleotidase activity in the whole cell homogenates.
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