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  • Title: Primary cutaneous anaplastic large cell lymphoma.
    Author: Brown RA, Fernandez-Pol S, Kim J.
    Journal: J Cutan Pathol; 2017 Jun; 44(6):570-577. PubMed ID: 28342276.
    Abstract:
    Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is a CD30+ lymphoproliferative disorder (LPD) of the skin with a relatively good prognosis in the absence of high-stage disease. CD30+ LPDs comprise approximately 25%-30% of primary cutaneous lymphomas and as a group represent the second most common clonal T-cell neoplasm of the skin behind mycosis fungoides. Diagnosis of PC-ALCL relies strongly on clinicopathologic correlation given the potential morphologic, clinical and molecular overlap with the other cutaneous CD30+ LPD, lymphomatoid papulosis, and more aggressive hematolymphoid neoplasms.
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