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  • Title: C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy.
    Author: Wan DH, Zheng BY, Ke MR, Duan JY, Zheng YQ, Yeh CK, Huang JD.
    Journal: Chem Commun (Camb); 2017 Apr 06; 53(29):4112-4115. PubMed ID: 28349131.
    Abstract:
    C-Phycocyanin (CPC) as a tumour-associated macrophage (TAM)-targeted photosensitiser has been first proved, and used as a vehicle of zinc phthalocyanine (ZnPc) to fabricate a ZnPc-CPC conjugate, which exhibits an efficient in vitro photodynamic activity, and selectively accumulates in tumour sites probably due to the affinity to TAM.
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