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  • Title: [Effect of various immunostimulants on 5-nucleotidase activity of macrophages of peritoneal exudate in the mouse].
    Author: Kirillicheva GB, Sinilova NG, Tumanian MA.
    Journal: Vopr Med Khim; 1988; 34(1):56-9. PubMed ID: 2835868.
    Abstract:
    All the immunostimulators studied, independently on their biological origin and chemical structure, decreased the 5-nucleotidase activity in macrophages of mice peritoneal exudate, thus indicating activation of these cells. The most distinct inhibition of the enzymatic activity in macrophages was induced by preparations of microbial origin. The decrease of the 5-nucleotidase activity in macrophages was observed in mice of CBA strain only after intraperitoneal administration of the preparations, while in non-linear animals--after subcutaneous or itraperitoneal injections.
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