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  • Title: A case report: Non-alcoholic Wernicke encephalopathy associated with polyneuropathy.
    Author: Liang H, Wu L, Liu LL, Han J, Zhu J, Jin T.
    Journal: J Int Med Res; 2017 Dec; 45(6):1794-1801. PubMed ID: 28367669.
    Abstract:
    We report a rare case of non-alcoholic Wernicke encephalopathy (WE) with polyneuropathy. A 24-year-old woman who had recently served a 4-month prison sentence and underwent a short period of dieting manifested slow response, weakness, language disorder and amnesia. Brain magnetic resonance imaging (MRI) revealed typical lesions of WE. Examination of nerve conduction velocity revealed sensory-motor axonal polyneuropathy. The patient was immediately treated with thiamine. Neurological symptoms were alleviated in a few days and abnormal signals were markedly decreased in a follow-up MRI 1 week later. Polyneuropathy symptoms ameliorated during hospital therapy and significantly improved after 4 months. This case suggests that WE may be associated with polyneuropathy in non-alcoholic patients. Early thiamine treatment in symptomatic patients may improve prognosis.
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