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Title: [Comparison of 2 immunoenzyme methods for the determination of anti-cytomegalovirus IgM]. Author: Billaudel S, Besse B, Mézière A, Courtieu AL. Journal: Ann Biol Clin (Paris); 1988; 46(2):119-22. PubMed ID: 2837928. Abstract: An antibody capture assay technique using a labeled antigen (Wellcome Laboratories) and an ELISA technique performed after elimination of serum IgG (Behring Laboratories) were assessed for determination of anti-cytomegalovirus IgM. Their specificity and sensitivity were compared in tests on 208 sera, some (60) of which had IgM rheumatoid factor, antinuclear antibodies or anti-Epstein-Barr virus antibodies. The other sera were analyzed relative to diagnosis of a cytomegalovirus infection. The antibody capture assay technique was slightly more sensitive than the ELISA technique but did not resolve all the specificity problems.[Abstract] [Full Text] [Related] [New Search]