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  • Title: [Directed biosynthesis of prostaglandin F2 alpha multiple labeled with tritium].
    Author: Iakusheva LA, Nagaev IIu, Lazurkina TIu, Shevchenko VP, Miagkova GI.
    Journal: Bioorg Khim; 1988 Feb; 14(2):232-5. PubMed ID: 2838030.
    Abstract:
    By selecting specific activators of PGF reductase and determining their optimal ratio, we have performed the directed biosynthesis of PGF2 alpha with a 45-50% yield. With the use of [5,6,8,9,11,12,14,15-3H8]arachidonic acid, multiple-labelled PGF2 alpha with molar radioactivity 6.1 TBe/mmol has been synthesised.
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