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  • Title: Infection by multiple viruses and lymphocyte abnormalities at the diagnosis of diabetes.
    Author: Surcel HM, Ilonen J, Käär ML, Hyöty H, Leinikki P.
    Journal: Acta Paediatr Scand; 1988 May; 77(3):471-4. PubMed ID: 2839003.
    Abstract:
    Evidence for an ongoing adenovirus infection and preceding EB and Coxsackie B virus infections was found in a 2-year-old boy at the diagnosis of insulin-dependent diabetes. An inverted T-helper/T-suppressor lymphocyte ratio and activation of T cells with a suppressor-cytotoxic phenotype were detected. A combination of multiple viral infections may be responsible for the rapid destruction of pancreatic beta cells in this case.
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