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  • Title: Comparison of imipenem and meropenem antibiotics for the MALDI-TOF MS detection of carbapenemase activity.
    Author: Rotova V, Papagiannitsis CC, Skalova A, Chudejova K, Hrabak J.
    Journal: J Microbiol Methods; 2017 Jun; 137():30-33. PubMed ID: 28390706.
    Abstract:
    A comparison of carbapenem molecules for the detection of carbapenemase-producing bacteria by MALDI-TOF MS showed that imipenem exhibited higher sensitivity (97%) and specificity (100%) scores for Pseudomonas aeruginosa than meropenem. However, meropenem was more efficient (98% sensitivity and 100% specificity) against Enterobacteriaceae.
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