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  • Title: Age related and lectin influenced changes of exoglycosidases activity in cultured chick embryonic skin fibroblasts.
    Author: Bodo M, Pezzetti F, Becchetti E, Orlacchio A, Evangelisti R, Carinci P.
    Journal: Cell Biol Int Rep; 1988 Jun; 12(6):459-64. PubMed ID: 2841029.
    Abstract:
    beta-N-acetyl-D-glucosaminidase, beta-N-acetyl-galactosaminidase and a beta-D-galactosidase activity was determined in untreated and lectins (ConA, PNA, SBA and WGA) treated chick embryonic skin fibroblasts at two incubation stages. Activity of all three glycosidases increased between 7 and 14 incubation days. ConA and WGA affected the levels of enzymatic activity; while SBA and PNA were uneffective. We discuss these findings in relation to a possible role of glycosidases in controlling mesenchymal GAG turnover.
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