MEDLINE/PubMed Journal Browser Search

Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

Title: [Long-term outcomes after cataract surgery in infants with congenital cataract].
Author: Qi JY, Xiao W, Wang MY, Zhao DX, Pu W.
Journal: Zhonghua Yan Ke Za Zhi; 2017 Apr 11; 53(4):266-273. PubMed ID: 28412799.
Abstract:
Objective: To observe the long-term outcomes after congenital cataract surgery performed prior to 36 months of age. Methods: A retrospective case study was conducted. Thirty-two cases (57 eyes) of congenital cataract were included from January 2004 to January 2012. All patients received intraocular lens (IOL) implantation with posterior continuous curvilinear capsulorhexies and anterior vitrectomy after cataract extraction and were followed up. At the last visit, the best corrected visual acuity (BCVA) was determined and postoperative complications were evaluated during follow-up with a longest time of 13 years. Non-normal distribution showed in median M (minimum and maximum). Data were analyzed by Kruskal Wallis single factor variance analysis and multiple comparison. The independent Mann-Witney U test was used to analyze non-normal distribution data. Results: There were thirty-two cases (57 eyes) of congenital cataract including 7 unilateral cases and 25 bilateral cases. The median age at cataract extraction was 6.0months; the median IOL implantation age was 28.0 months and the median duration of follow-up after cataract extraction was 67.0 months. The median postoperative BCVA was (LogMAR) 0.52. Unilateral and bilateral cataract postoperative BCVA difference had no statistical significance (U=107, P>0.05). Patients received cataract surgery in 2 to 4 months, the postoperative BCVA was better than in 5 to 8 months. The difference was statistical significance (H=-15.33, P<0.05). BCVA after IOL implantation before 24 months were significantly better than after 30 months. The difference had statistical significance(H=-20.61,-20.78, P<0.05). Postoperative complications were posterior capsular opacity (5 eyes; 8.77%), glaucoma (2 eyes; 3.51%), strabismus (17 eyes; 29.82%) and nystagmus (30 eyes; 52.63%). Conclusions: Most infantile cataract surgeries performed prior to 36 mouths of life together with the implantation of IOL can achieve good visual acuity. No serious complications occurred. (Chin J Ophthalmol, 2017, 53: 266-273). 目的： 观察婴幼儿先天性白内障患者白内障吸除术后的长期治疗效果。 方法： 回顾性系列病例研究。观察2004年1月至2012年1月中国医科大学附属盛京医院眼科收治的婴幼儿先天性白内障患儿32例（57只眼），所有患儿均接受了白内障吸除、后囊膜及前段玻璃体切除手术，均根据眼球大小分为一期白内障吸除、二期IOL植入以及同期白内障吸除联合IOL植入。术后连续随访最长达13年。对末次检查时的最佳矫正视力（BCVA），术眼出现的主要并发症进行系统的临床观察。采用SPSS 21.0统计软件进行数据处理。非正态分布以中位数M（最小值，最大值）表示。采用Kruskal-Wallis单因素方差分析多重比较和独立样本Mann-Witney U检验进行非参数检验。 结果： 32例（57只眼）先天性白内障患儿单眼7例、双眼25例，白内障吸除手术年龄中位数是6.0个月（2.0，35.0）；IOL植入年龄中位数是28.0个月（16.0，44.0）；白内障吸除术后随访时间中位数是67.0个月（31.0，159.0）；术后BCVA（LogMAR）中位数是0.52（0.10，1.40）；单眼BCVA（LogMAR）1.00（0.30，1.30）、双眼BCVA（LogMAR）0.49（0.10，1.40），差异无统计学意义（U=107，P>0.05）。出生后2~4个月接受手术者术后BCVA显著优于出生后5~8个月接受手术者，差异有统计学意义（H=-15.33，P<0.05）；出生后16~18个月、19~24个月植入IOL术后的BCVA均优于31~44个月的BCVA，差异均有统计学意义（H=-20.61、-20.78，P<0.05）。后囊膜混浊5只眼（4例），占8.77%；青光眼2只眼（2例），占3.51%；术后斜视17只眼（15例），占29.82%；眼球震颤30只眼（19例），占52.63%。 结论： 绝大多数先天性白内障患儿在婴幼儿时期行白内障吸除及IOL植入手术可获得长期良好的生活视力，无一例发生严重并发症。（中华眼科杂志，2017，53：266-273）.

[Abstract] [Full Text] [Related] [New Search]