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  • Title: [Establishment of a T lymphoid cell line producing a retrovirus of HTLV-I type, from peripheral blood of a patient with tropical spastic paraparesis].
    Author: Gessain A, Saal F, Vilette D, Lasneret J, Giron ML, Sigaux F, Gout O, Emanoil-Ravier R, de Thé G, Periés J.
    Journal: C R Acad Sci III; 1988; 307(2):53-8. PubMed ID: 2843260.
    Abstract:
    HTLV-I, the causative agent of Adult T cell Leukemia, has recently been found to be associated with chronic neuromyelopathies common in tropical areas and in Japan. We report here the establishment of a lymphoid T cell line from peripheral blood lymphocytes of a patient with Tropical Spastic Paraparesis. This cell line produces a retrovirus whose morphologic, antigenic and genetic characteristics show no detectable difference from the leukemogenic prototype of HTLV-I.
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