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  • Title: Heat shock-induced accumulation of ubiquitin mRNA in Xenopus laevis embryos is developmentally regulated.
    Author: Ovsenek N, Heikkila JJ.
    Journal: Dev Biol; 1988 Oct; 129(2):582-5. PubMed ID: 2843405.
    Abstract:
    Exposure of Xenopus laevis embryos to heat shock induced the accumulation of ubiquitin mRNA (size range, 1.7-3.5 kb) in a developmental stage-dependent fashion. While constitutive ubiquitin transcripts were detectable throughout development, heat shock-induced accumulation did not occur until the fine-cell blastula stage. Continuous exposure of neurulae to heat shock (33 degrees C) induced a transient accumulation of ubiquitin mRNA with peak levels occurring after 2 hr. Finally, placement of Xenopus neurulae at 22 degrees C after a 1-hr heat shock at 33 degrees C produced a decrease in ubiquitin mRNA levels to near control levels by 24 hr.
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