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  • Title: Structure and genomic organization of I elements involved in I-R hybrid dysgenesis in Drosophila melanogaster.
    Author: Crozatier M, Vaury C, Busseau I, Pelisson A, Bucheton A.
    Journal: Nucleic Acids Res; 1988 Oct 11; 16(19):9199-213. PubMed ID: 2845368.
    Abstract:
    I-R hybrid dysgenesis in D. melanogaster is controlled by transposable elements known as I factors which terminate at their 3' ends by an A-rich sequence. Inducer strains contain active I factors. Both reactive and inducer stocks possess defective I elements. We have cloned various I elements from both categories of strains. The I elements having recently transposed in inducer strains have a structure closely related to that of active I factors. However we have isolated one such I element that is truncated at its 5' end. The I elements common to reactive and inducer strains are affected by various rearrangements and many point mutations. They do not appear to be simple derivatives of complete I factors.
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