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  • Title: Spontaneous fracture of the femur due to osteomyelitis caused by the Streptococcus anginosus group.
    Author: Janssen EHCC, de Bree LCJ, Kant KM, van Wijngaarden P.
    Journal: Neth J Med; 2017 Apr; 75(3):121-124. PubMed ID: 28469049.
    Abstract:
    A 57-year-old man was admitted because of pain in the right upper leg due to an osteolytic lesion of the femoral bone which was complicated by a spontaneous fracture. At first a malignancy was suspected. However, blood and bone cultures revealed the Streptococcus anginosus group. A diagnosis of acute osteomyelitis was made. In spite of extensive antibiotic and surgical treatment the patient developed severe septic shock with multiple organ failure and died. In the case of a pathological fracture, one should consider the broad differential diagnosis, including osteomyelitis, which should lead to a laboratory work-up and imaging studies. When bone biopsy for histological analysis is necessary, a microbiological culture to look for osteomyelitis should always be performed.
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